diff --git a/defaults/main.yml b/defaults/main.yml
index e74d997..6ba0114 100644
--- a/defaults/main.yml
+++ b/defaults/main.yml
@@ -56,6 +56,11 @@ venv_default_pip_packages: []
 # into the venv.
 venv_pip_packages: []
 
+# Don't use the site-wide PIP configuration file when
+# upgrading PIP (some operating systems have issued
+# with upgrades w/ extra-index-urls)
+venv_pip_upgrade_noconf: false
+
 # A list of constraints to be applied when building
 # or installing python packages.
 venv_build_constraints: []
diff --git a/tasks/python_venv_install.yml b/tasks/python_venv_install.yml
index 514a328..7f8f573 100644
--- a/tasks/python_venv_install.yml
+++ b/tasks/python_venv_install.yml
@@ -100,6 +100,8 @@
       --log /var/log/python_venv_build.log
       {{ venv_default_pip_install_args }}
       {{ venv_pip_install_args }}
+  environment:
+    PIP_CONFIG_FILE: "{{ (venv_pip_upgrade_noconf | bool) | ternary('/dev/null', '') }}"
   register: _update_virtualenv_packages
   until: _update_virtualenv_packages is success
   retries: 5
diff --git a/tasks/python_venv_wheel_build.yml b/tasks/python_venv_wheel_build.yml
index 7ef3978..d1f5c25 100644
--- a/tasks/python_venv_wheel_build.yml
+++ b/tasks/python_venv_wheel_build.yml
@@ -99,6 +99,8 @@
           --find-links {{ venv_build_host_wheel_path }}/
           --log /var/log/python_venv_build.log
           {{ venv_pip_build_args }}
+      environment:
+        PIP_CONFIG_FILE: "{{ (venv_pip_upgrade_noconf | bool) | ternary('/dev/null', '') }}"
       register: _update_virtualenv_packages
       until: _update_virtualenv_packages is success
       retries: 5