diff --git a/oslo_db/sqlalchemy/exc_filters.py b/oslo_db/sqlalchemy/exc_filters.py
index 9fb81c3..3040edc 100644
--- a/oslo_db/sqlalchemy/exc_filters.py
+++ b/oslo_db/sqlalchemy/exc_filters.py
@@ -387,6 +387,7 @@ def _raise_operational_errors_directly_filter(operational_error,
 
 @filters("mysql", sqla_exc.OperationalError, r".*\(.*(?:2002|2003|2006|2013|1047)")  # noqa
 @filters("mysql", sqla_exc.InternalError, r".*\(.*(?:1927)")  # noqa
+@filters("mysql", sqla_exc.InternalError, r".*Packet sequence number wrong")  # noqa
 @filters("postgresql", sqla_exc.OperationalError, r".*could not connect to server")  # noqa
 @filters("ibm_db_sa", sqla_exc.OperationalError, r".*(?:30081)")
 def _is_db_connection_error(operational_error, match, engine_name,
diff --git a/oslo_db/tests/sqlalchemy/test_exc_filters.py b/oslo_db/tests/sqlalchemy/test_exc_filters.py
index 0894c3d..558cca8 100644
--- a/oslo_db/tests/sqlalchemy/test_exc_filters.py
+++ b/oslo_db/tests/sqlalchemy/test_exc_filters.py
@@ -1195,6 +1195,14 @@ class TestDBDisconnected(TestsExceptionFilter):
                 is_disconnect=False
             )
 
+    def test_packet_sequence_wrong_error(self):
+        self._test_ping_listener_disconnected(
+            "mysql",
+            self.InternalError(
+                'Packet sequence number wrong - got 35 expected 1'),
+            is_disconnect=False
+        )
+
     def test_mysql_ping_listener_disconnected(self):
         for code in [2006, 2013, 2014, 2045, 2055]:
             self._test_ping_listener_disconnected(