diff --git a/ironic_inspector/conductor/manager.py b/ironic_inspector/conductor/manager.py
index 55cf897fb..884ad4883 100644
--- a/ironic_inspector/conductor/manager.py
+++ b/ironic_inspector/conductor/manager.py
@@ -81,11 +81,13 @@ class ConductorManager(object):
         driver.init_filter()
 
         periodic_clean_up_ = periodics.periodic(
-            spacing=CONF.clean_up_period
+            spacing=CONF.clean_up_period,
+            enabled=(CONF.clean_up_period != 0)
         )(periodic_clean_up)
 
         sync_with_ironic_ = periodics.periodic(
-            spacing=CONF.clean_up_period
+            spacing=CONF.clean_up_period,
+            enabled=(CONF.clean_up_period != 0)
         )(sync_with_ironic)
 
         callables = [(periodic_clean_up_, None, None),
diff --git a/ironic_inspector/conf/default.py b/ironic_inspector/conf/default.py
index 643eca7e5..0bda7969b 100644
--- a/ironic_inspector/conf/default.py
+++ b/ironic_inspector/conf/default.py
@@ -55,8 +55,15 @@ _OPTS = [
                       'failed, set to 0 to disable.')),
     cfg.IntOpt('clean_up_period',
                default=60,
+               min=0,
                help=_('Amount of time in seconds, after which repeat clean up '
-                      'of timed out nodes and old nodes status information.')),
+                      'of timed out nodes and old nodes status information. '
+                      'WARNING: If set to a value of 0, then the periodic '
+                      'task is disabled and inspector will not sync with '
+                      'ironic to complete the internal clean-up process. '
+                      'Not advisable if the deployment uses a PXE filter, '
+                      'and will result in the ironic-inspector ceasing '
+                      'periodic cleanup activities.')),
     cfg.BoolOpt('use_ssl',
                 default=False,
                 help=_('SSL Enabled/Disabled')),
@@ -89,7 +96,7 @@ _OPTS = [
                        'endpoint via multicast DNS.')),
     cfg.BoolOpt('standalone', default=True,
                 help=_('Whether to run ironic-inspector as a standalone '
-                       'service. It\'s EXPERIMENTAL to set to False.'))
+                       'service. It\'s EXPERIMENTAL to set to False.')),
 ]
 
 
diff --git a/releasenotes/notes/ability-to-turn-off-periodic-sync-5309ff2aa8a9ec14.yaml b/releasenotes/notes/ability-to-turn-off-periodic-sync-5309ff2aa8a9ec14.yaml
new file mode 100644
index 000000000..79ff9a927
--- /dev/null
+++ b/releasenotes/notes/ability-to-turn-off-periodic-sync-5309ff2aa8a9ec14.yaml
@@ -0,0 +1,8 @@
+---
+features:
+  - |
+    Adds the ability for periodic clean-up and synchronization tasks with
+    ``ironic`` to be able to be disabled by setting the
+    ``[DEFAULT]clean_up_period`` to a value of ``0``. This is intended for
+    "stand-alone" operators only as it may result in unexpected behaviors if
+    used in a non-standalone environment.