diff --git a/.zuul.yaml b/.zuul.yaml
index 0c1cad33..42d8b055 100644
--- a/.zuul.yaml
+++ b/.zuul.yaml
@@ -3,7 +3,6 @@
       - check-requirements
       - lib-forward-testing-python3
       - openstack-lower-constraints-jobs
-      - openstack-python35-jobs
       - openstack-python3-ussuri-jobs
       - openstacksdk-functional-tips
       - openstacksdk-tox-tips
diff --git a/py35-upper-constraints.txt b/py35-upper-constraints.txt
deleted file mode 100644
index 6d7ec716..00000000
--- a/py35-upper-constraints.txt
+++ /dev/null
@@ -1,6 +0,0 @@
-oslo.i18n===3.25.1
-debtcollector===1.22.0
-oslotest===3.9.0
-reno===2.11.3
-oslo.config===7.0.0
-oslo.utils===3.42.1
diff --git a/releasenotes/notes/drop-python-3.5-362bb9d47f830353.yaml b/releasenotes/notes/drop-python-3.5-362bb9d47f830353.yaml
new file mode 100644
index 00000000..a78c85f4
--- /dev/null
+++ b/releasenotes/notes/drop-python-3.5-362bb9d47f830353.yaml
@@ -0,0 +1,4 @@
+---
+upgrade:
+  - |
+    Python 3.5 is no longer supported.
diff --git a/setup.cfg b/setup.cfg
index 89d14a81..573737a7 100644
--- a/setup.cfg
+++ b/setup.cfg
@@ -6,7 +6,7 @@ description-file =
 author = OpenStack
 author-email = openstack-discuss@lists.openstack.org
 home-page = https://docs.openstack.org/keystoneauth/latest/
-python-requires = >=3.5
+python-requires = >=3.6
 classifier =
     Environment :: OpenStack
     Intended Audience :: Information Technology
@@ -17,7 +17,6 @@ classifier =
     Programming Language :: Python :: Implementation :: CPython
     Programming Language :: Python :: 3 :: Only
     Programming Language :: Python :: 3
-    Programming Language :: Python :: 3.5
     Programming Language :: Python :: 3.6
     Programming Language :: Python :: 3.7
     Programming Language :: Python :: 3.8
diff --git a/tox.ini b/tox.ini
index dc703134..97ff0cec 100644
--- a/tox.ini
+++ b/tox.ini
@@ -18,12 +18,6 @@ whitelist_externals =
   bash
 basepython = python3
 
-[testenv:py35]
-deps =
-  -c{toxinidir}/py35-upper-constraints.txt
-  -r{toxinidir}/requirements.txt
-  -r{toxinidir}/test-requirements.txt
-
 [testenv:pep8]
 commands =
   flake8