diff --git a/contrib/pools-management/subports.py b/contrib/pools-management/subports.py
index d6f86de95..86eca7d10 100644
--- a/contrib/pools-management/subports.py
+++ b/contrib/pools-management/subports.py
@@ -13,10 +13,10 @@
 # limitations under the License.
 
 import argparse
+from http import client as httplib
 import socket
 
 from oslo_serialization import jsonutils
-from six.moves import http_client as httplib
 
 from kuryr_kubernetes import constants
 
diff --git a/kuryr_kubernetes/cni/api.py b/kuryr_kubernetes/cni/api.py
index 8a3544abc..b5d696522 100644
--- a/kuryr_kubernetes/cni/api.py
+++ b/kuryr_kubernetes/cni/api.py
@@ -15,16 +15,14 @@
 
 
 import abc
-import six
-from six.moves import http_client as httplib
+from http import client as httplib
 import traceback
 
-import requests
-
 from kuryr.lib._i18n import _
 from os_vif.objects import base
 from oslo_log import log as logging
 from oslo_serialization import jsonutils
+import requests
 
 from kuryr_kubernetes import config
 from kuryr_kubernetes import constants as k_const
@@ -33,8 +31,7 @@ from kuryr_kubernetes import exceptions as k_exc
 LOG = logging.getLogger(__name__)
 
 
-@six.add_metaclass(abc.ABCMeta)
-class CNIRunner(object):
+class CNIRunner(object, metaclass=abc.ABCMeta):
     # TODO(ivc): extend SUPPORTED_VERSIONS and format output based on
     # requested params.CNI_VERSION and/or params.config.cniVersion
     VERSION = '0.3.1'
diff --git a/kuryr_kubernetes/cni/binding/base.py b/kuryr_kubernetes/cni/binding/base.py
index 2f490ed5e..97b61cbe4 100644
--- a/kuryr_kubernetes/cni/binding/base.py
+++ b/kuryr_kubernetes/cni/binding/base.py
@@ -15,7 +15,6 @@
 
 import abc
 import errno
-import six
 
 import os_vif
 from oslo_log import log as logging
@@ -30,8 +29,7 @@ _BINDING_NAMESPACE = 'kuryr_kubernetes.cni.binding'
 LOG = logging.getLogger(__name__)
 
 
-@six.add_metaclass(abc.ABCMeta)
-class BaseBindingDriver(object):
+class BaseBindingDriver(object, metaclass=abc.ABCMeta):
     """Interface to attach ports to pods."""
 
     def _remove_ifaces(self, ipdb, ifnames, netns='host'):
diff --git a/kuryr_kubernetes/cni/binding/nested.py b/kuryr_kubernetes/cni/binding/nested.py
index 2a9e81e23..db1231616 100644
--- a/kuryr_kubernetes/cni/binding/nested.py
+++ b/kuryr_kubernetes/cni/binding/nested.py
@@ -14,7 +14,6 @@
 
 import abc
 import errno
-import six
 
 from oslo_log import log as logging
 import pyroute2
@@ -32,8 +31,8 @@ MACVLAN_MODE_BRIDGE = 'bridge'
 LOG = logging.getLogger(__name__)
 
 
-@six.add_metaclass(abc.ABCMeta)
-class NestedDriver(health.HealthHandler, b_base.BaseBindingDriver):
+class NestedDriver(health.HealthHandler, b_base.BaseBindingDriver,
+                   metaclass=abc.ABCMeta):
 
     def __init__(self):
         super(NestedDriver, self).__init__()
diff --git a/kuryr_kubernetes/cni/daemon/service.py b/kuryr_kubernetes/cni/daemon/service.py
index dd9b9cd60..435735be6 100644
--- a/kuryr_kubernetes/cni/daemon/service.py
+++ b/kuryr_kubernetes/cni/daemon/service.py
@@ -13,9 +13,9 @@
 # limitations under the License.
 
 from ctypes import c_bool
+from http import client as httplib
 import multiprocessing
 import os
-from six.moves import http_client as httplib
 import socket
 import sys
 import threading
diff --git a/kuryr_kubernetes/cni/handlers.py b/kuryr_kubernetes/cni/handlers.py
index 1519b3244..aded36895 100644
--- a/kuryr_kubernetes/cni/handlers.py
+++ b/kuryr_kubernetes/cni/handlers.py
@@ -14,7 +14,6 @@
 #    under the License.
 
 import abc
-import six
 
 from os_vif import objects as obj_vif
 from oslo_log import log as logging
@@ -28,8 +27,7 @@ from kuryr_kubernetes import utils
 LOG = logging.getLogger(__name__)
 
 
-@six.add_metaclass(abc.ABCMeta)
-class CNIHandlerBase(k8s_base.ResourceEventHandler):
+class CNIHandlerBase(k8s_base.ResourceEventHandler, metaclass=abc.ABCMeta):
     OBJECT_KIND = k_const.K8S_OBJ_POD
 
     def __init__(self, cni, on_done):
diff --git a/kuryr_kubernetes/cni/health.py b/kuryr_kubernetes/cni/health.py
index 345d9b2f8..93b524ae7 100644
--- a/kuryr_kubernetes/cni/health.py
+++ b/kuryr_kubernetes/cni/health.py
@@ -10,8 +10,8 @@
 # See the License for the specific language governing permissions and
 # limitations under the License.
 
+from http import client as httplib
 import os
-from six.moves import http_client as httplib
 
 from flask import Flask
 from pyroute2 import IPDB
diff --git a/kuryr_kubernetes/cni/main.py b/kuryr_kubernetes/cni/main.py
index 0811b82fb..0957cd384 100644
--- a/kuryr_kubernetes/cni/main.py
+++ b/kuryr_kubernetes/cni/main.py
@@ -15,7 +15,6 @@
 
 import os
 import signal
-import six
 import sys
 
 import os_vif
@@ -35,10 +34,7 @@ _CNI_TIMEOUT = 180
 
 
 def run():
-    if six.PY3:
-        d = jsonutils.load(sys.stdin.buffer)
-    else:
-        d = jsonutils.load(sys.stdin)
+    d = jsonutils.load(sys.stdin.buffer)
     cni_conf = utils.CNIConfig(d)
     args = (['--config-file', cni_conf.kuryr_conf] if 'kuryr_conf' in d
             else [])
diff --git a/kuryr_kubernetes/cni/plugins/base.py b/kuryr_kubernetes/cni/plugins/base.py
index 3e1811789..5d9ccb51e 100644
--- a/kuryr_kubernetes/cni/plugins/base.py
+++ b/kuryr_kubernetes/cni/plugins/base.py
@@ -15,11 +15,9 @@
 
 
 import abc
-import six
 
 
-@six.add_metaclass(abc.ABCMeta)
-class CNIPlugin(object):
+class CNIPlugin(object, metaclass=abc.ABCMeta):
 
     @abc.abstractmethod
     def add(self, params):
diff --git a/kuryr_kubernetes/controller/drivers/base.py b/kuryr_kubernetes/controller/drivers/base.py
index 3aaef2b23..08bacbfd1 100644
--- a/kuryr_kubernetes/controller/drivers/base.py
+++ b/kuryr_kubernetes/controller/drivers/base.py
@@ -14,7 +14,6 @@
 #    under the License.
 
 import abc
-import six
 
 from kuryr.lib._i18n import _
 from stevedore import driver as stv_driver
@@ -38,8 +37,7 @@ class DriverBase(object):
 
     Usage example:
 
-        @six.add_metaclass(abc.ABCMeta)
-        class SomeDriverInterface(DriverBase):
+        class SomeDriverInterface(DriverBase, metaclass=abc.ABCMeta):
             ALIAS = 'driver_alias'
 
             @abc.abstractmethod
@@ -93,8 +91,7 @@ class DriverBase(object):
         return self.__class__.__name__
 
 
-@six.add_metaclass(abc.ABCMeta)
-class PodProjectDriver(DriverBase):
+class PodProjectDriver(DriverBase, metaclass=abc.ABCMeta):
     """Provides an OpenStack project ID for Kubernetes Pod ports."""
 
     ALIAS = 'pod_project'
@@ -110,8 +107,7 @@ class PodProjectDriver(DriverBase):
         raise NotImplementedError()
 
 
-@six.add_metaclass(abc.ABCMeta)
-class ServiceProjectDriver(DriverBase):
+class ServiceProjectDriver(DriverBase, metaclass=abc.ABCMeta):
     """Provides an OpenStack project ID for Kubernetes Services."""
 
     ALIAS = 'service_project'
@@ -127,8 +123,7 @@ class ServiceProjectDriver(DriverBase):
         raise NotImplementedError()
 
 
-@six.add_metaclass(abc.ABCMeta)
-class NamespaceProjectDriver(DriverBase):
+class NamespaceProjectDriver(DriverBase, metaclass=abc.ABCMeta):
     """Provides an OpenStack project ID for Kubernetes Namespace."""
 
     ALIAS = 'namespace_project'
@@ -144,8 +139,7 @@ class NamespaceProjectDriver(DriverBase):
         raise NotImplementedError()
 
 
-@six.add_metaclass(abc.ABCMeta)
-class PodSubnetsDriver(DriverBase):
+class PodSubnetsDriver(DriverBase, metaclass=abc.ABCMeta):
     """Provides subnets for Kubernetes Pods."""
 
     ALIAS = 'pod_subnets'
@@ -202,8 +196,7 @@ class PodSubnetsDriver(DriverBase):
         raise NotImplementedError()
 
 
-@six.add_metaclass(abc.ABCMeta)
-class ServiceSubnetsDriver(DriverBase):
+class ServiceSubnetsDriver(DriverBase, metaclass=abc.ABCMeta):
     """Provides subnets for Kubernetes Services."""
 
     ALIAS = 'service_subnets'
@@ -222,8 +215,7 @@ class ServiceSubnetsDriver(DriverBase):
         raise NotImplementedError()
 
 
-@six.add_metaclass(abc.ABCMeta)
-class PodSecurityGroupsDriver(DriverBase):
+class PodSecurityGroupsDriver(DriverBase, metaclass=abc.ABCMeta):
     """Provides security groups for Kubernetes Pods."""
 
     ALIAS = 'pod_security_groups'
@@ -287,8 +279,7 @@ class PodSecurityGroupsDriver(DriverBase):
         raise NotImplementedError()
 
 
-@six.add_metaclass(abc.ABCMeta)
-class ServiceSecurityGroupsDriver(DriverBase):
+class ServiceSecurityGroupsDriver(DriverBase, metaclass=abc.ABCMeta):
     """Provides security groups for Kubernetes Services."""
 
     ALIAS = 'service_security_groups'
@@ -304,8 +295,7 @@ class ServiceSecurityGroupsDriver(DriverBase):
         raise NotImplementedError()
 
 
-@six.add_metaclass(abc.ABCMeta)
-class PodVIFDriver(DriverBase):
+class PodVIFDriver(DriverBase, metaclass=abc.ABCMeta):
     """Manages Neutron ports to provide VIFs for Kubernetes Pods."""
 
     ALIAS = 'pod_vif'
@@ -433,8 +423,7 @@ class PodVIFDriver(DriverBase):
         raise NotImplementedError()
 
 
-@six.add_metaclass(abc.ABCMeta)
-class MultiVIFDriver(DriverBase):
+class MultiVIFDriver(DriverBase, metaclass=abc.ABCMeta):
     """Manages additional ports of Kubernetes Pods."""
 
     ALIAS = 'multi_vif'
@@ -626,8 +615,7 @@ class LBaaSDriver(DriverBase):
         raise NotImplementedError()
 
 
-@six.add_metaclass(abc.ABCMeta)
-class VIFPoolDriver(PodVIFDriver):
+class VIFPoolDriver(PodVIFDriver, metaclass=abc.ABCMeta):
     """Manages Pool of Neutron ports to provide VIFs for Kubernetes Pods."""
 
     ALIAS = 'vif_pool'
@@ -657,8 +645,7 @@ class VIFPoolDriver(PodVIFDriver):
         raise NotImplementedError()
 
 
-@six.add_metaclass(abc.ABCMeta)
-class ServicePubIpDriver(DriverBase):
+class ServicePubIpDriver(DriverBase, metaclass=abc.ABCMeta):
     """Manages loadbalancerIP/public ip for neutron lbaas."""
 
     ALIAS = 'service_public_ip'
@@ -705,8 +692,7 @@ class ServicePubIpDriver(DriverBase):
         """
 
 
-@six.add_metaclass(abc.ABCMeta)
-class NetworkPolicyDriver(DriverBase):
+class NetworkPolicyDriver(DriverBase, metaclass=abc.ABCMeta):
     """Provide network-policy for pods"""
 
     ALIAS = 'network_policy'
@@ -777,8 +763,7 @@ class NetworkPolicyDriver(DriverBase):
         raise NotImplementedError()
 
 
-@six.add_metaclass(abc.ABCMeta)
-class NetworkPolicyProjectDriver(DriverBase):
+class NetworkPolicyProjectDriver(DriverBase, metaclass=abc.ABCMeta):
     """Get an OpenStack project id for K8s network policies"""
 
     ALIAS = 'network_policy_project'
diff --git a/kuryr_kubernetes/controller/drivers/nested_vif.py b/kuryr_kubernetes/controller/drivers/nested_vif.py
index b250c1392..f22081925 100644
--- a/kuryr_kubernetes/controller/drivers/nested_vif.py
+++ b/kuryr_kubernetes/controller/drivers/nested_vif.py
@@ -13,7 +13,6 @@
 #    under the License.
 
 import abc
-import six
 
 from kuryr.lib import exceptions as kl_exc
 from openstack import exceptions as os_exc
@@ -27,8 +26,8 @@ from kuryr_kubernetes.controller.drivers import neutron_vif
 LOG = logging.getLogger(__name__)
 
 
-@six.add_metaclass(abc.ABCMeta)
-class NestedPodVIFDriver(neutron_vif.NeutronPodVIFDriver):
+class NestedPodVIFDriver(neutron_vif.NeutronPodVIFDriver,
+                         metaclass=abc.ABCMeta):
     """Skeletal handler driver for VIFs for Nested Pods."""
 
     def _get_parent_port_by_host_ip(self, node_fixed_ip):
diff --git a/kuryr_kubernetes/controller/drivers/public_ip.py b/kuryr_kubernetes/controller/drivers/public_ip.py
index 1b3a48183..f9d55ab90 100644
--- a/kuryr_kubernetes/controller/drivers/public_ip.py
+++ b/kuryr_kubernetes/controller/drivers/public_ip.py
@@ -13,7 +13,6 @@
 #    License for the specific language governing permissions and limitations
 #    under the License.
 import abc
-import six
 
 from openstack import exceptions as os_exc
 from oslo_log import log as logging
@@ -24,8 +23,7 @@ from kuryr_kubernetes.controller.drivers import utils
 LOG = logging.getLogger(__name__)
 
 
-@six.add_metaclass(abc.ABCMeta)
-class BasePubIpDriver(object):
+class BasePubIpDriver(object, metaclass=abc.ABCMeta):
     """Base class for public IP functionality."""
 
     @abc.abstractmethod
diff --git a/kuryr_kubernetes/controller/drivers/utils.py b/kuryr_kubernetes/controller/drivers/utils.py
index 9b4b7d42d..59a912c97 100644
--- a/kuryr_kubernetes/controller/drivers/utils.py
+++ b/kuryr_kubernetes/controller/drivers/utils.py
@@ -13,12 +13,13 @@
 #    License for the specific language governing permissions and limitations
 #    under the License.
 
+import urllib
+
 from openstack import exceptions as os_exc
 from oslo_cache import core as cache
 from oslo_config import cfg
 from oslo_log import log
 from oslo_serialization import jsonutils
-from six.moves.urllib import parse
 
 from kuryr_kubernetes import clients
 from kuryr_kubernetes import constants
@@ -117,10 +118,10 @@ def get_pods(selector, namespace=None):
         if exps:
             exps = ', '.join(format_expression(exp) for exp in exps)
             if labels:
-                expressions = parse.quote("," + exps)
+                expressions = urllib.parse.quote("," + exps)
                 labels += expressions
             else:
-                labels = parse.quote(exps)
+                labels = urllib.parse.quote(exps)
 
     if namespace:
         pods = kubernetes.get(
@@ -149,10 +150,10 @@ def get_namespaces(selector):
     if exps:
         exps = ', '.join(format_expression(exp) for exp in exps)
         if labels:
-            expressions = parse.quote("," + exps)
+            expressions = urllib.parse.quote("," + exps)
             labels += expressions
         else:
-            labels = parse.quote(exps)
+            labels = urllib.parse.quote(exps)
 
     namespaces = kubernetes.get(
         '{}/namespaces?labelSelector={}'.format(
@@ -177,7 +178,7 @@ def format_expression(expression):
 
 
 def replace_encoded_characters(labels):
-    labels = parse.urlencode(labels)
+    labels = urllib.parse.urlencode(labels)
     # NOTE(ltomasbo): K8s API does not accept &, so we need to AND
     # the matchLabels with ',' or '%2C' instead
     labels = labels.replace('&', ',')
diff --git a/kuryr_kubernetes/controller/drivers/vif_pool.py b/kuryr_kubernetes/controller/drivers/vif_pool.py
index 9fd9c4271..34eda4e26 100644
--- a/kuryr_kubernetes/controller/drivers/vif_pool.py
+++ b/kuryr_kubernetes/controller/drivers/vif_pool.py
@@ -17,7 +17,6 @@ import abc
 import collections
 import eventlet
 import os
-import six
 import time
 
 from kuryr.lib._i18n import _
@@ -130,8 +129,7 @@ class NoopVIFPool(base.VIFPoolDriver):
         pass
 
 
-@six.add_metaclass(abc.ABCMeta)
-class BaseVIFPool(base.VIFPoolDriver):
+class BaseVIFPool(base.VIFPoolDriver, metaclass=abc.ABCMeta):
     """Skeletal pool driver.
 
     In order to handle the pools of ports, a few dicts are used:
diff --git a/kuryr_kubernetes/controller/managers/health.py b/kuryr_kubernetes/controller/managers/health.py
index 07eecc447..25128bbb1 100644
--- a/kuryr_kubernetes/controller/managers/health.py
+++ b/kuryr_kubernetes/controller/managers/health.py
@@ -12,8 +12,8 @@
 # See the License for the specific language governing permissions and
 # limitations under the License.
 
+from http import client as httplib
 import os
-from six.moves import http_client as httplib
 
 from flask import Flask
 from oslo_config import cfg
diff --git a/kuryr_kubernetes/controller/managers/pool.py b/kuryr_kubernetes/controller/managers/pool.py
index 99e17788b..8ea64e1cf 100644
--- a/kuryr_kubernetes/controller/managers/pool.py
+++ b/kuryr_kubernetes/controller/managers/pool.py
@@ -12,11 +12,11 @@
 # See the License for the specific language governing permissions and
 # limitations under the License.
 
+from http import server
 import os
+import socketserver
 import threading
 
-from six.moves.BaseHTTPServer import BaseHTTPRequestHandler
-from six.moves.socketserver import ThreadingUnixStreamServer
 
 from openstack import exceptions as os_exc
 from oslo_config import cfg as oslo_cfg
@@ -41,11 +41,11 @@ pool_manager_opts = [
 oslo_cfg.CONF.register_opts(pool_manager_opts, "pool_manager")
 
 
-class UnixDomainHttpServer(ThreadingUnixStreamServer):
+class UnixDomainHttpServer(socketserver.ThreadingUnixStreamServer):
     pass
 
 
-class RequestHandler(BaseHTTPRequestHandler):
+class RequestHandler(server.BaseHTTPRequestHandler):
     protocol = "HTTP/1.0"
 
     def do_POST(self):
diff --git a/kuryr_kubernetes/controller/service.py b/kuryr_kubernetes/controller/service.py
index 7c166c769..1a0956bc3 100644
--- a/kuryr_kubernetes/controller/service.py
+++ b/kuryr_kubernetes/controller/service.py
@@ -14,7 +14,6 @@
 #    under the License.
 
 import functools
-import six
 import sys
 
 import os_vif
@@ -72,9 +71,8 @@ class KuryrK8sServiceMeta(type(service.Service),
     pass
 
 
-class KuryrK8sService(six.with_metaclass(KuryrK8sServiceMeta,
-                                         service.Service,
-                                         periodic_task.PeriodicTasks)):
+class KuryrK8sService(service.Service, periodic_task.PeriodicTasks,
+                      metaclass=KuryrK8sServiceMeta):
     """Kuryr-Kubernetes controller Service."""
 
     def __init__(self):
diff --git a/kuryr_kubernetes/handlers/asynchronous.py b/kuryr_kubernetes/handlers/asynchronous.py
index 599f522e6..9f20a2e9e 100755
--- a/kuryr_kubernetes/handlers/asynchronous.py
+++ b/kuryr_kubernetes/handlers/asynchronous.py
@@ -14,7 +14,7 @@
 #    under the License.
 
 import itertools
-from six.moves import queue as six_queue
+import queue as py_queue
 import time
 
 from oslo_log import log as logging
@@ -54,7 +54,7 @@ class Async(base.EventHandler):
         try:
             queue = self._queues[group]
         except KeyError:
-            queue = six_queue.Queue(self._queue_depth)
+            queue = py_queue.Queue(self._queue_depth)
             self._queues[group] = queue
             thread = self._thread_group.add_thread(self._run, group, queue)
             thread.link(self._done, group)
@@ -68,7 +68,7 @@ class Async(base.EventHandler):
             # avoid tests getting stuck in infinite loops)
             try:
                 event = queue.get(timeout=self._grace_period)
-            except six_queue.Empty:
+            except py_queue.Empty:
                 break
             # FIXME(ivc): temporary workaround to skip stale events
             # If K8s updates resource while the handler is processing it,
diff --git a/kuryr_kubernetes/handlers/base.py b/kuryr_kubernetes/handlers/base.py
index 18b77cdfb..62c23f9e4 100644
--- a/kuryr_kubernetes/handlers/base.py
+++ b/kuryr_kubernetes/handlers/base.py
@@ -14,11 +14,9 @@
 #    under the License.
 
 import abc
-import six
 
 
-@six.add_metaclass(abc.ABCMeta)
-class EventHandler(object):
+class EventHandler(object, metaclass=abc.ABCMeta):
     """Base class for event handlers."""
 
     @abc.abstractmethod
diff --git a/kuryr_kubernetes/handlers/dispatch.py b/kuryr_kubernetes/handlers/dispatch.py
index 43acc93f9..4bf023740 100644
--- a/kuryr_kubernetes/handlers/dispatch.py
+++ b/kuryr_kubernetes/handlers/dispatch.py
@@ -14,7 +14,6 @@
 #    under the License.
 
 import abc
-import six
 
 from oslo_log import log as logging
 
@@ -71,8 +70,7 @@ class Dispatcher(h_base.EventHandler):
             handler(event)
 
 
-@six.add_metaclass(abc.ABCMeta)
-class EventConsumer(h_base.EventHandler):
+class EventConsumer(h_base.EventHandler, metaclass=abc.ABCMeta):
     """Consumes events matching specified predicates.
 
     EventConsumer is an interface for all event handlers that are to be
@@ -92,8 +90,7 @@ class EventConsumer(h_base.EventHandler):
         raise NotImplementedError()
 
 
-@six.add_metaclass(abc.ABCMeta)
-class EventPipeline(h_base.EventHandler):
+class EventPipeline(h_base.EventHandler, metaclass=abc.ABCMeta):
     """Serves as an entry-point for event handling.
 
     Implementing subclasses should override `_wrap_dispatcher` and/or
diff --git a/kuryr_kubernetes/objects/base.py b/kuryr_kubernetes/objects/base.py
index af31f2405..75498d05e 100644
--- a/kuryr_kubernetes/objects/base.py
+++ b/kuryr_kubernetes/objects/base.py
@@ -14,14 +14,13 @@
 #    under the License.
 
 import abc
-import six
 
 from oslo_versionedobjects import base as obj_base
 
 
-@six.add_metaclass(abc.ABCMeta)
 class KuryrK8sObjectBase(obj_base.VersionedObject,
-                         obj_base.ComparableVersionedObject):
+                         obj_base.ComparableVersionedObject,
+                         metaclass=abc.ABCMeta):
 
     OBJ_PROJECT_NAMESPACE = 'kuryr_kubernetes'
 
diff --git a/kuryr_kubernetes/tests/unit/cmd/test_status.py b/kuryr_kubernetes/tests/unit/cmd/test_status.py
index dbd2b84bc..7ef2f7e00 100644
--- a/kuryr_kubernetes/tests/unit/cmd/test_status.py
+++ b/kuryr_kubernetes/tests/unit/cmd/test_status.py
@@ -12,10 +12,10 @@
 #    License for the specific language governing permissions and limitations
 #    under the License.
 
-import mock
+import io
 
+import mock
 from oslo_serialization import jsonutils
-import six
 
 from kuryr_kubernetes.cmd import status
 from kuryr_kubernetes import constants
@@ -62,7 +62,7 @@ class TestStatusCmd(test_base.TestCase):
         obj = self.cmd._get_annotation(pod)
         self.assertEqual(mock_obj, obj)
 
-    @mock.patch('sys.stdout', new_callable=six.StringIO)
+    @mock.patch('sys.stdout', new_callable=io.StringIO)
     def _test_upgrade_check(self, code, code_name, m_stdout):
         method_success_m = mock.Mock()
         method_success_m.return_value = status.UpgradeCheckResult(0, 'foo')
diff --git a/kuryr_kubernetes/tests/unit/cni/test_api.py b/kuryr_kubernetes/tests/unit/cni/test_api.py
index ba5da4ff5..21fb27a3c 100644
--- a/kuryr_kubernetes/tests/unit/cni/test_api.py
+++ b/kuryr_kubernetes/tests/unit/cni/test_api.py
@@ -13,13 +13,12 @@
 #    License for the specific language governing permissions and limitations
 #    under the License.
 
+from io import StringIO
+
 import mock
-from six import StringIO
-
-import requests
-
 from oslo_config import cfg
 from oslo_serialization import jsonutils
+import requests
 
 from kuryr_kubernetes.cni import api
 from kuryr_kubernetes.tests import base as test_base
diff --git a/kuryr_kubernetes/tests/unit/controller/drivers/test_base.py b/kuryr_kubernetes/tests/unit/controller/drivers/test_base.py
index c16c9d58b..eae15b497 100644
--- a/kuryr_kubernetes/tests/unit/controller/drivers/test_base.py
+++ b/kuryr_kubernetes/tests/unit/controller/drivers/test_base.py
@@ -14,15 +14,14 @@
 #    under the License.
 
 import abc
+
 import mock
-import six
 
 from kuryr_kubernetes.controller.drivers import base as d_base
 from kuryr_kubernetes.tests import base as test_base
 
 
-@six.add_metaclass(abc.ABCMeta)
-class _TestDriver(d_base.DriverBase):
+class _TestDriver(d_base.DriverBase, metaclass=abc.ABCMeta):
     ALIAS = 'test_alias'
 
     @abc.abstractmethod
diff --git a/kuryr_kubernetes/tests/unit/handlers/test_asynchronous.py b/kuryr_kubernetes/tests/unit/handlers/test_asynchronous.py
index 8095e3f8e..90e0cebf3 100644
--- a/kuryr_kubernetes/tests/unit/handlers/test_asynchronous.py
+++ b/kuryr_kubernetes/tests/unit/handlers/test_asynchronous.py
@@ -14,7 +14,7 @@
 #    under the License.
 
 import mock
-from six.moves import queue as six_queue
+import queue
 
 from kuryr_kubernetes.handlers import asynchronous as h_async
 from kuryr_kubernetes.tests import base as test_base
@@ -37,7 +37,7 @@ class TestAsyncHandler(test_base.TestCase):
         self.assertEqual({group: m_queue}, async_handler._queues)
         m_queue.put.assert_called_once_with(event)
 
-    @mock.patch('six.moves.queue.Queue')
+    @mock.patch('queue.Queue')
     def test_call_new(self, m_queue_type):
         event = mock.sentinel.event
         group = mock.sentinel.group
@@ -85,7 +85,7 @@ class TestAsyncHandler(test_base.TestCase):
         group = mock.sentinel.group
         m_queue = mock.Mock()
         m_queue.empty.return_value = True
-        m_queue.get.side_effect = events + [six_queue.Empty()]
+        m_queue.get.side_effect = events + [queue.Empty()]
         m_handler = mock.Mock()
         m_count.return_value = list(range(5))
         async_handler = h_async.Async(m_handler, mock.Mock(), mock.Mock())
@@ -102,7 +102,7 @@ class TestAsyncHandler(test_base.TestCase):
         group = mock.sentinel.group
         m_queue = mock.Mock()
         m_queue.empty.side_effect = [False, True, True]
-        m_queue.get.side_effect = events + [six_queue.Empty()]
+        m_queue.get.side_effect = events + [queue.Empty()]
         m_handler = mock.Mock()
         m_count.return_value = list(range(5))
         async_handler = h_async.Async(m_handler, mock.Mock(), mock.Mock())
diff --git a/lower-constraints.txt b/lower-constraints.txt
index 5bb36c7db..15906e981 100644
--- a/lower-constraints.txt
+++ b/lower-constraints.txt
@@ -113,7 +113,6 @@ rfc3986==1.1.0
 Routes==2.4.1
 setproctitle==1.1.10
 simplejson==3.13.2
-six==1.10.0
 snowballstemmer==1.2.1
 Sphinx==1.6.2
 sphinxcontrib-websupport==1.0.1
diff --git a/requirements.txt b/requirements.txt
index c93ed6117..33d32e20c 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -21,7 +21,6 @@ os-vif>=1.12.0 # Apache-2.0
 PrettyTable<0.8,>=0.7.2  # BSD
 pyroute2>=0.5.7;sys_platform!='win32' # Apache-2.0 (+ dual licensed GPL2)
 retrying!=1.3.0,>=1.2.3 # Apache-2.0
-six>=1.10.0 # MIT
 stevedore>=1.20.0 # Apache-2.0
 grpcio>=1.12.0 # Apache-2.0
 protobuf>=3.6.0 # 3-Clause BSD