diff --git a/etc/octavia.conf b/etc/octavia.conf
index 10afbb6e11..c82ca21ac3 100644
--- a/etc/octavia.conf
+++ b/etc/octavia.conf
@@ -68,6 +68,10 @@
 # see https://cheatsheetseries.owasp.org/cheatsheets/TLS_Cipher_String_Cheat_Sheet.html
 # default_pool_ciphers = TLS_AES_256_GCM_SHA384:TLS_CHACHA20_POLY1305_SHA256:TLS_AES_128_GCM_SHA256:DHE-RSA-AES256-GCM-SHA384:DHE-RSA-AES128-GCM-SHA256:ECDHE-RSA-AES256-GCM-SHA384:ECDHE-RSA-AES128-GCM-SHA256:DHE-RSA-AES256-SHA256:DHE-RSA-AES128-SHA256:ECDHE-RSA-AES256-SHA384:ECDHE-RSA-AES128-SHA256
 
+# Colon-separated list of disallowed ciphers. Ciphers specified here will not be
+# allowed on listeners, pools, or the default values for either.
+# tls_cipher_blacklist =
+
 [database]
 # This line MUST be changed to actually run the plugin.
 # Example:
diff --git a/octavia/api/v2/controllers/listener.py b/octavia/api/v2/controllers/listener.py
index 7bac00f747..62ca98b68c 100644
--- a/octavia/api/v2/controllers/listener.py
+++ b/octavia/api/v2/controllers/listener.py
@@ -33,6 +33,7 @@ from octavia.common import data_models
 from octavia.common import exceptions
 from octavia.common import stats
 from octavia.common import utils as common_utils
+from octavia.common import validate
 from octavia.db import api as db_api
 from octavia.db import prepare as db_prepare
 from octavia.i18n import _
@@ -223,6 +224,15 @@ class ListenersController(base.BaseController):
                 "A client authentication CA reference is required to "
                 "specify a client authentication revocation list."))
 
+        # Check TLS cipher blacklist
+        if 'tls_ciphers' in listener_dict and listener_dict['tls_ciphers']:
+            rejected_ciphers = validate.check_cipher_blacklist(
+                listener_dict['tls_ciphers'])
+            if rejected_ciphers:
+                raise exceptions.ValidationException(detail=_(
+                    'The following ciphers have been blacklisted by an '
+                    'administrator: ' + ', '.join(rejected_ciphers)))
+
         # Validate the TLS containers
         sni_containers = listener_dict.pop('sni_containers', [])
         tls_refs = [sni['tls_container_id'] for sni in sni_containers]
@@ -475,6 +485,15 @@ class ListenersController(base.BaseController):
             self._validate_cidr_compatible_with_vip(
                 vip_address, listener.allowed_cidrs)
 
+        # Check TLS cipher blacklist
+        if listener.tls_ciphers:
+            rejected_ciphers = validate.check_cipher_blacklist(
+                listener.tls_ciphers)
+            if rejected_ciphers:
+                raise exceptions.ValidationException(detail=_(
+                    'The following ciphers have been blacklisted by an '
+                    'administrator: ' + ', '.join(rejected_ciphers)))
+
     def _set_default_on_none(self, listener):
         """Reset settings to their default values if None/null was passed in
 
diff --git a/octavia/api/v2/controllers/pool.py b/octavia/api/v2/controllers/pool.py
index 1ad210f7ef..b000c61f3e 100644
--- a/octavia/api/v2/controllers/pool.py
+++ b/octavia/api/v2/controllers/pool.py
@@ -122,6 +122,15 @@ class PoolsController(base.BaseController):
                 pool_dict.get('ca_tls_certificate_id'),
                 pool_dict.get('crl_container_id', None))
 
+        # Check TLS cipher blacklist
+        if 'tls_ciphers' in pool_dict and pool_dict['tls_ciphers']:
+            rejected_ciphers = validate.check_cipher_blacklist(
+                pool_dict['tls_ciphers'])
+            if rejected_ciphers:
+                raise exceptions.ValidationException(detail=_(
+                    'The following ciphers have been blacklisted by an '
+                    'administrator: ' + ', '.join(rejected_ciphers)))
+
         try:
             return self.repositories.create_pool_on_load_balancer(
                 lock_session, pool_dict,
@@ -377,6 +386,15 @@ class PoolsController(base.BaseController):
         if ca_ref:
             self._validate_client_ca_and_crl_refs(ca_ref, crl_ref)
 
+        # Check TLS cipher blacklist
+        if pool.tls_ciphers:
+            rejected_ciphers = validate.check_cipher_blacklist(
+                pool.tls_ciphers)
+            if rejected_ciphers:
+                raise exceptions.ValidationException(detail=_(
+                    "The following ciphers have been blacklisted by an "
+                    "administrator: " + ', '.join(rejected_ciphers)))
+
     @wsme_pecan.wsexpose(pool_types.PoolRootResponse, wtypes.text,
                          body=pool_types.PoolRootPut, status_code=200)
     def put(self, id, pool_):
diff --git a/octavia/common/config.py b/octavia/common/config.py
index 5bb5f6435b..502f451ffd 100644
--- a/octavia/common/config.py
+++ b/octavia/common/config.py
@@ -31,6 +31,7 @@ import oslo_messaging as messaging
 from octavia.certificates.common import local
 from octavia.common import constants
 from octavia.common import utils
+from octavia.common import validate
 from octavia.i18n import _
 from octavia import version
 
@@ -112,6 +113,9 @@ api_opts = [
                default=constants.CIPHERS_OWASP_SUITE_B,
                help=_("Default OpenSSL cipher string (colon-separated) for "
                       "new TLS-enabled pools.")),
+    cfg.StrOpt('tls_cipher_blacklist', default='',
+               help=_("Colon separated list of OpenSSL ciphers. "
+                      "Usage of these ciphers will be blocked."))
 ]
 
 # Options only used by the amphora agent
@@ -822,6 +826,7 @@ def init(args, **kwargs):
              **kwargs)
     handle_deprecation_compatibility()
     setup_remote_debugger()
+    validate.check_default_ciphers_blacklist_conflict()
 
 
 def setup_logging(conf):
diff --git a/octavia/common/validate.py b/octavia/common/validate.py
index dc8e49690f..60e458aee8 100644
--- a/octavia/common/validate.py
+++ b/octavia/common/validate.py
@@ -433,3 +433,29 @@ def is_flavor_spares_compatible(flavor):
         if flavor.get(constants.COMPUTE_FLAVOR, None):
             return False
     return True
+
+
+def check_cipher_blacklist(cipherstring):
+    ciphers = cipherstring.split(':')
+    blacklist = CONF.api_settings.tls_cipher_blacklist.split(':')
+    rejected = []
+    for cipher in ciphers:
+        if cipher in blacklist:
+            rejected.append(cipher)
+    return rejected
+
+
+def check_default_ciphers_blacklist_conflict():
+    listener_rejected = check_cipher_blacklist(
+        CONF.api_settings.default_listener_ciphers)
+    if listener_rejected:
+        raise exceptions.ValidationException(
+            detail=_('Default listener ciphers conflict with blacklist. '
+                     'Conflicting ciphers: ' + ', '.join(listener_rejected)))
+
+    pool_rejected = check_cipher_blacklist(
+        CONF.api_settings.default_pool_ciphers)
+    if pool_rejected:
+        raise exceptions.ValidationException(
+            detail=_('Default pool ciphers conflict with blacklist. '
+                     'Conflicting ciphers: ' + ', '.join(pool_rejected)))
diff --git a/octavia/tests/unit/common/test_validations.py b/octavia/tests/unit/common/test_validations.py
index 6e7d2cd7b1..d7d2e1d8f3 100644
--- a/octavia/tests/unit/common/test_validations.py
+++ b/octavia/tests/unit/common/test_validations.py
@@ -460,3 +460,13 @@ class TestValidations(base.TestCase):
         self.assertTrue(validate.is_flavor_spares_compatible(compat_flavor))
         self.assertFalse(
             validate.is_flavor_spares_compatible(not_compat_flavor))
+
+    def test_check_default_ciphers_blacklist_conflict(self):
+        self.conf.config(group='api_settings',
+                         tls_cipher_blacklist='PSK-AES128-CBC-SHA')
+        self.conf.config(group='api_settings',
+                         default_listener_ciphers='ECDHE-ECDSA-AES256-SHA:'
+                         'PSK-AES128-CBC-SHA:TLS_AES_256_GCM_SHA384')
+
+        self.assertRaises(exceptions.ValidationException,
+                          validate.check_default_ciphers_blacklist_conflict)
diff --git a/releasenotes/notes/tls-cipher-blacklist-b5a23ca38149f3b8.yaml b/releasenotes/notes/tls-cipher-blacklist-b5a23ca38149f3b8.yaml
new file mode 100644
index 0000000000..4b82b0ca7a
--- /dev/null
+++ b/releasenotes/notes/tls-cipher-blacklist-b5a23ca38149f3b8.yaml
@@ -0,0 +1,6 @@
+---
+features:
+  - |
+    Added ``tls_cipher_blacklist`` to ``octavia.conf``. Listeners, pools, and
+    the default values for either will be blocked from using any of these ciphers.
+    By default, no ciphers are blacklisted.