diff --git a/glance/Chart.yaml b/glance/Chart.yaml
index f1b43edbf1..6ba0bb66ee 100644
--- a/glance/Chart.yaml
+++ b/glance/Chart.yaml
@@ -14,7 +14,7 @@ apiVersion: v1
 appVersion: v1.0.0
 description: OpenStack-Helm Glance
 name: glance
-version: 0.4.20
+version: 0.4.21
 home: https://docs.openstack.org/glance/latest/
 icon: https://www.openstack.org/themes/openstack/images/project-mascots/Glance/OpenStack_Project_Glance_vertical.png
 sources:
diff --git a/glance/templates/bin/_glance-api.sh.tpl b/glance/templates/bin/_glance-api.sh.tpl
index 9d427b60a2..a9018c2b4f 100644
--- a/glance/templates/bin/_glance-api.sh.tpl
+++ b/glance/templates/bin/_glance-api.sh.tpl
@@ -18,8 +18,7 @@ set -ex
 COMMAND="${@:-start}"
 
 function start () {
-  exec glance-api \
-        --config-file /etc/glance/glance-api.conf
+  exec uwsgi --ini /etc/glance/glance-api-uwsgi.ini
 }
 
 function stop () {
diff --git a/glance/templates/configmap-etc.yaml b/glance/templates/configmap-etc.yaml
index 0ee260614e..5a5f1c2814 100644
--- a/glance/templates/configmap-etc.yaml
+++ b/glance/templates/configmap-etc.yaml
@@ -100,6 +100,15 @@ limitations under the License.
 {{- $_ := tuple "image" "service" "api" . | include "helm-toolkit.endpoints.endpoint_port_lookup" | set .Values.conf.glance.DEFAULT "bind_port" -}}
 {{- end -}}
 
+{{- if empty .Values.conf.glance_api_uwsgi.uwsgi.processes -}}
+{{- $_ := set .Values.conf.glance_api_uwsgi.uwsgi "processes" .Values.conf.glance.DEFAULT.workers -}}
+{{- end -}}
+{{- if empty (index .Values.conf.glance_api_uwsgi.uwsgi "http-socket") -}}
+{{- $http_socket_port := tuple "image" "service" "api" . | include "helm-toolkit.endpoints.endpoint_port_lookup" | toString }}
+{{- $http_socket := printf "0.0.0.0:%s" $http_socket_port }}
+{{- $_ := set .Values.conf.glance_api_uwsgi.uwsgi "http-socket" $http_socket -}}
+{{- end -}}
+
 {{- if and (empty .Values.conf.logging.handler_fluent) (has "fluent" .Values.conf.logging.handlers.keys) -}}
 {{- $fluentd_host := tuple "fluentd" "internal" $envAll | include "helm-toolkit.endpoints.hostname_namespaced_endpoint_lookup" }}
 {{- $fluentd_port := tuple "fluentd" "internal" "service" $envAll | include "helm-toolkit.endpoints.endpoint_port_lookup" }}
@@ -141,6 +150,7 @@ type: Opaque
 data:
   rally_tests.yaml: {{ toYaml .Values.conf.rally_tests.tests | b64enc }}
   glance-api.conf: {{ include "helm-toolkit.utils.to_oslo_conf" .Values.conf.glance | b64enc }}
+  glance-api-uwsgi.ini: {{ include "helm-toolkit.utils.to_oslo_conf" .Values.conf.glance_api_uwsgi | b64enc }}
   logging.conf: {{ include "helm-toolkit.utils.to_oslo_conf" .Values.conf.logging | b64enc }}
   glance-api-paste.ini: {{ include "helm-toolkit.utils.to_ini" .Values.conf.paste | b64enc }}
   policy.yaml: {{ toYaml .Values.conf.policy | b64enc }}
diff --git a/glance/templates/deployment-api.yaml b/glance/templates/deployment-api.yaml
index e836a61fce..bfeaf26bff 100644
--- a/glance/templates/deployment-api.yaml
+++ b/glance/templates/deployment-api.yaml
@@ -214,6 +214,10 @@ spec:
               mountPath: /etc/glance/glance-api.conf
               subPath: glance-api.conf
               readOnly: true
+            - name: glance-etc
+              mountPath: /etc/glance/glance-api-uwsgi.ini
+              subPath: glance-api-uwsgi.ini
+              readOnly: true
             {{- if .Values.conf.glance.DEFAULT.log_config_append }}
             - name: glance-etc
               mountPath: {{ .Values.conf.glance.DEFAULT.log_config_append }}
diff --git a/glance/values.yaml b/glance/values.yaml
index 098c46ffbb..d2c3f50415 100644
--- a/glance/values.yaml
+++ b/glance/values.yaml
@@ -389,6 +389,22 @@ conf:
         priority: 0
         apply-to: all
         pattern: '^(?!(amq\.|reply_)).*'
+  glance_api_uwsgi:
+    uwsgi:
+      add-header: "Connection: close"
+      buffer-size: 65535
+      die-on-term: true
+      enable-threads: true
+      exit-on-reload: false
+      hook-master-start: unix_signal:15 gracefully_kill_them_all
+      lazy-apps: true
+      log-x-forwarded-for: true
+      master: true
+      procname-prefix-spaced: "glance-api:"
+      route-user-agent: '^kube-probe.* donotlog:'
+      thunder-lock: true
+      worker-reload-mercy: 80
+      wsgi-file: /var/lib/openstack/bin/glance-wsgi-api
 
 network:
   api:
@@ -883,14 +899,14 @@ pod:
         readiness:
           enabled: true
           params:
-            periodSeconds: 15
-            timeoutSeconds: 10
+            periodSeconds: 10
+            timeoutSeconds: 5
         liveness:
           enabled: true
           params:
-            initialDelaySeconds: 30
-            periodSeconds: 15
-            timeoutSeconds: 10
+            initialDelaySeconds: 5
+            periodSeconds: 10
+            timeoutSeconds: 5
   resources:
     enabled: false
     api:
diff --git a/glance/values_overrides/tls.yaml b/glance/values_overrides/tls.yaml
index 385f9d054a..d1aa35ad02 100644
--- a/glance/values_overrides/tls.yaml
+++ b/glance/values_overrides/tls.yaml
@@ -4,8 +4,6 @@ images:
     nginx: docker.io/nginx:1.18.0
 conf:
   glance:
-    DEFAULT:
-      bind_host: 127.0.0.1
     keystone_authtoken:
       cafile: /etc/glance/certs/ca.crt
     glance_store:
@@ -16,6 +14,9 @@ conf:
       ssl_ca_file: /etc/rabbitmq/certs/ca.crt
       ssl_cert_file: /etc/rabbitmq/certs/tls.crt
       ssl_key_file: /etc/rabbitmq/certs/tls.key
+  glance_api_uwsgi:
+    uwsgi:
+      http-socket: 127.0.0.1:9292
   nginx: |
     worker_processes 1;
     daemon off;
diff --git a/releasenotes/notes/glance.yaml b/releasenotes/notes/glance.yaml
index 70433f7511..3a36199b7e 100644
--- a/releasenotes/notes/glance.yaml
+++ b/releasenotes/notes/glance.yaml
@@ -54,4 +54,5 @@ glance:
   - 0.4.18 Enable custom annotations for Openstack pods
   - 0.4.19 Add 2024.1 overrides
   - 0.4.20 Add readiness probe initial delay
+  - 0.4.21 Use uWSGI
 ...