diff --git a/doc/source/user/api.rst b/doc/source/user/api.rst
index c449158..03111e2 100644
--- a/doc/source/user/api.rst
+++ b/doc/source/user/api.rst
@@ -39,8 +39,7 @@ Five ways to add a new trace point.
         def _traced_only_if_trace_private_true(self):
              pass
 
-    @six.add_metaclass(profiler.TracedMeta)
-    class RpcManagerClass(object):
+    class RpcManagerClass(object, metaclass=profiler.TracedMeta):
         __trace_args__ = {'name': 'rpc',
                           'info': None,
                           'hide_args': False,
diff --git a/lower-constraints.txt b/lower-constraints.txt
index 2ced6ac..994e394 100644
--- a/lower-constraints.txt
+++ b/lower-constraints.txt
@@ -15,7 +15,6 @@ pymongo===3.0.2
 redis===2.10.0
 reno==3.1.0
 requests===2.14.2
-six===1.10.0
 Sphinx===2.0.0
 stestr==2.0.0
 testtools===2.2.0
diff --git a/osprofiler/_utils.py b/osprofiler/_utils.py
index c23d600..7563fb5 100644
--- a/osprofiler/_utils.py
+++ b/osprofiler/_utils.py
@@ -22,7 +22,6 @@ import uuid
 
 from oslo_utils import secretutils
 from oslo_utils import uuidutils
-import six
 
 
 def split(text, strip=True):
@@ -32,7 +31,7 @@ def split(text, strip=True):
     """
     if isinstance(text, (tuple, list)):
         return text
-    if not isinstance(text, six.string_types):
+    if not isinstance(text, str):
         raise TypeError("Unknown how to split '%s': %s" % (text, type(text)))
     if strip:
         return [t.strip() for t in text.split(",") if t.strip()]
@@ -45,9 +44,9 @@ def binary_encode(text, encoding="utf-8"):
 
     Does nothing if text not unicode string.
     """
-    if isinstance(text, six.binary_type):
+    if isinstance(text, bytes):
         return text
-    elif isinstance(text, six.text_type):
+    elif isinstance(text, str):
         return text.encode(encoding)
     else:
         raise TypeError("Expected binary or string type")
@@ -58,9 +57,9 @@ def binary_decode(data, encoding="utf-8"):
 
     Does nothing if data is already unicode string.
     """
-    if isinstance(data, six.binary_type):
+    if isinstance(data, bytes):
         return data.decode(encoding)
-    elif isinstance(data, six.text_type):
+    elif isinstance(data, str):
         return data
     else:
         raise TypeError("Expected binary or string type")
@@ -154,7 +153,7 @@ def import_modules_from_package(package):
 def shorten_id(span_id):
     """Convert from uuid4 to 64 bit id for OpenTracing"""
     int64_max = (1 << 64) - 1
-    if isinstance(span_id, six.integer_types):
+    if isinstance(span_id, int):
         return span_id & int64_max
     try:
         short_id = uuid.UUID(span_id).int & int64_max
diff --git a/osprofiler/cmd/commands.py b/osprofiler/cmd/commands.py
index c4750a5..ab80c9e 100644
--- a/osprofiler/cmd/commands.py
+++ b/osprofiler/cmd/commands.py
@@ -19,7 +19,6 @@ import os
 from oslo_utils import encodeutils
 from oslo_utils import uuidutils
 import prettytable
-import six
 
 from osprofiler.cmd import cliutils
 from osprofiler.drivers import base
@@ -188,7 +187,4 @@ class TraceCommands(BaseCommand):
         for trace in traces:
             row = [trace[field] for field in fields]
             pretty_table.add_row(row)
-        if six.PY3:
-            print(encodeutils.safe_encode(pretty_table.get_string()).decode())
-        else:
-            print(encodeutils.safe_encode(pretty_table.get_string()))
+        print(encodeutils.safe_encode(pretty_table.get_string()).decode())
diff --git a/osprofiler/drivers/base.py b/osprofiler/drivers/base.py
index bb0dc7e..99b37b1 100644
--- a/osprofiler/drivers/base.py
+++ b/osprofiler/drivers/base.py
@@ -15,8 +15,7 @@
 
 import datetime
 import logging
-
-import six.moves.urllib.parse as urlparse
+from urllib import parse as urlparse
 
 from osprofiler import _utils
 
diff --git a/osprofiler/drivers/elasticsearch_driver.py b/osprofiler/drivers/elasticsearch_driver.py
index 2e80fe0..d4a6b3d 100644
--- a/osprofiler/drivers/elasticsearch_driver.py
+++ b/osprofiler/drivers/elasticsearch_driver.py
@@ -13,8 +13,9 @@
 #    License for the specific language governing permissions and limitations
 #    under the License.
 
+from urllib import parse as parser
+
 from oslo_config import cfg
-import six.moves.urllib.parse as parser
 
 from osprofiler.drivers import base
 from osprofiler import exc
diff --git a/osprofiler/drivers/jaeger.py b/osprofiler/drivers/jaeger.py
index 262f6a6..3f263b2 100644
--- a/osprofiler/drivers/jaeger.py
+++ b/osprofiler/drivers/jaeger.py
@@ -16,10 +16,10 @@
 import collections
 import datetime
 import time
+from urllib import parse as parser
 
 from oslo_config import cfg
 from oslo_serialization import jsonutils
-import six.moves.urllib.parse as parser
 
 from osprofiler import _utils as utils
 from osprofiler.drivers import base
diff --git a/osprofiler/drivers/loginsight.py b/osprofiler/drivers/loginsight.py
index 4e875ae..f59518b 100644
--- a/osprofiler/drivers/loginsight.py
+++ b/osprofiler/drivers/loginsight.py
@@ -19,11 +19,11 @@ Classes to use VMware vRealize Log Insight as the trace data store.
 
 import json
 import logging as log
+from urllib import parse as urlparse
 
 import netaddr
 from oslo_concurrency.lockutils import synchronized
 import requests
-import six.moves.urllib.parse as urlparse
 
 from osprofiler.drivers import base
 from osprofiler import exc
diff --git a/osprofiler/drivers/redis_driver.py b/osprofiler/drivers/redis_driver.py
index 4c1fc62..48436cf 100644
--- a/osprofiler/drivers/redis_driver.py
+++ b/osprofiler/drivers/redis_driver.py
@@ -14,10 +14,11 @@
 #    License for the specific language governing permissions and limitations
 #    under the License.
 
+from urllib import parse as parser
+
 from debtcollector import removals
 from oslo_config import cfg
 from oslo_serialization import jsonutils
-import six.moves.urllib.parse as parser
 
 from osprofiler.drivers import base
 from osprofiler import exc
diff --git a/osprofiler/hacking/checks.py b/osprofiler/hacking/checks.py
index 2723210..3ac17b5 100644
--- a/osprofiler/hacking/checks.py
+++ b/osprofiler/hacking/checks.py
@@ -364,7 +364,7 @@ def check_using_unicode(logical_line, filename):
 
     if re.search(r"\bunicode\(", logical_line):
         yield (0, "N353 'unicode' function is absent in python3. Please "
-                  "use 'six.text_type' instead.")
+                  "use 'str' instead.")
 
 
 @core.flake8ext
diff --git a/osprofiler/profiler.py b/osprofiler/profiler.py
index 7949f0e..5406b39 100644
--- a/osprofiler/profiler.py
+++ b/osprofiler/profiler.py
@@ -22,7 +22,6 @@ import threading
 
 from oslo_utils import reflection
 from oslo_utils import uuidutils
-import six
 
 from osprofiler import _utils as utils
 from osprofiler import notifier
@@ -161,7 +160,7 @@ def trace(name, info=None, hide_args=False, hide_result=True,
             except Exception as ex:
                 stop_info = {
                     "etype": reflection.get_class_name(ex),
-                    "message": six.text_type(ex)
+                    "message": str(ex)
                 }
                 raise
             else:
@@ -274,8 +273,7 @@ class TracedMeta(type):
 
     Possible usage:
 
-    >>>  @six.add_metaclass(profiler.TracedMeta)
-    >>>  class RpcManagerClass(object):
+    >>>  class RpcManagerClass(object, metaclass=profiler.TracedMeta):
     >>>      __trace_args__ = {'name': 'rpc',
     >>>                        'info': None,
     >>>                        'hide_args': False,
diff --git a/osprofiler/tests/unit/cmd/test_shell.py b/osprofiler/tests/unit/cmd/test_shell.py
index 845d8d9..26be88e 100644
--- a/osprofiler/tests/unit/cmd/test_shell.py
+++ b/osprofiler/tests/unit/cmd/test_shell.py
@@ -13,13 +13,13 @@
 #    License for the specific language governing permissions and limitations
 #    under the License.
 
+import io
 import json
 import os
 import sys
 from unittest import mock
 
 import ddt
-import six
 
 from osprofiler.cmd import shell
 from osprofiler import exc
@@ -43,7 +43,7 @@ class ShellTestCase(test.TestCase):
         cmd = "trace show --connection-string redis:// %s" % self.TRACE_ID
         return cmd if format_ is None else "%s --%s" % (cmd, format_)
 
-    @mock.patch("sys.stdout", six.StringIO())
+    @mock.patch("sys.stdout", io.StringIO())
     @mock.patch("osprofiler.cmd.shell.OSProfilerShell")
     def test_shell_main(self, mock_shell):
         mock_shell.side_effect = exc.CommandError("some_message")
@@ -99,7 +99,7 @@ class ShellTestCase(test.TestCase):
         }
         return notifications
 
-    @mock.patch("sys.stdout", six.StringIO())
+    @mock.patch("sys.stdout", io.StringIO())
     @mock.patch("osprofiler.drivers.redis_driver.Redis.get_report")
     def test_trace_show_in_json(self, mock_get):
         notifications = self._create_mock_notifications()
@@ -110,7 +110,7 @@ class ShellTestCase(test.TestCase):
                                              separators=(",", ": "),),
                          sys.stdout.getvalue())
 
-    @mock.patch("sys.stdout", six.StringIO())
+    @mock.patch("sys.stdout", io.StringIO())
     @mock.patch("osprofiler.drivers.redis_driver.Redis.get_report")
     def test_trace_show_in_html(self, mock_get):
         notifications = self._create_mock_notifications()
@@ -139,7 +139,7 @@ class ShellTestCase(test.TestCase):
                                                separators=(",", ": ")),
                              sys.stdout.getvalue())
 
-    @mock.patch("sys.stdout", six.StringIO())
+    @mock.patch("sys.stdout", io.StringIO())
     @mock.patch("osprofiler.drivers.redis_driver.Redis.get_report")
     def test_trace_show_write_to_file(self, mock_get):
         notifications = self._create_mock_notifications()
diff --git a/osprofiler/tests/unit/test_profiler.py b/osprofiler/tests/unit/test_profiler.py
index 0f0fcb5..ec24046 100644
--- a/osprofiler/tests/unit/test_profiler.py
+++ b/osprofiler/tests/unit/test_profiler.py
@@ -19,7 +19,6 @@ import datetime
 import re
 from unittest import mock
 
-import six
 
 from osprofiler import profiler
 from osprofiler.tests import test
@@ -462,7 +461,6 @@ class TraceClsDecoratorTestCase(test.TestCase):
                 #                  - and FakeTraceStatic.method4 in PY3
                 "name":
                     "osprofiler.tests.unit.test_profiler"
-                    ".method4" if six.PY2 else
                     "osprofiler.tests.unit.test_profiler.FakeTraceStatic"
                     ".method4",
                 "args": str((25,)),
@@ -490,8 +488,7 @@ class TraceClsDecoratorTestCase(test.TestCase):
         self.assertFalse(mock_stop.called)
 
 
-@six.add_metaclass(profiler.TracedMeta)
-class FakeTraceWithMetaclassBase(object):
+class FakeTraceWithMetaclassBase(object, metaclass=profiler.TracedMeta):
     __trace_args__ = {"name": "rpc",
                       "info": {"a": 10}}
 
@@ -534,8 +531,8 @@ class TraceWithMetaclassTestCase(test.TestCase):
 
     def test_no_name_exception(self):
         def define_class_with_no_name():
-            @six.add_metaclass(profiler.TracedMeta)
-            class FakeTraceWithMetaclassNoName(FakeTracedCls):
+            class FakeTraceWithMetaclassNoName(FakeTracedCls,
+                                               metaclass=profiler.TracedMeta):
                 pass
         self.assertRaises(TypeError, define_class_with_no_name, 1)
 
diff --git a/osprofiler/web.py b/osprofiler/web.py
index 20875b1..c83d68a 100644
--- a/osprofiler/web.py
+++ b/osprofiler/web.py
@@ -13,7 +13,6 @@
 #    License for the specific language governing permissions and limitations
 #    under the License.
 
-import six
 import webob.dec
 
 from osprofiler import _utils as utils
@@ -98,7 +97,7 @@ class WsgiMiddleware(object):
     def _trace_is_valid(self, trace_info):
         if not isinstance(trace_info, dict):
             return False
-        trace_keys = set(six.iterkeys(trace_info))
+        trace_keys = set(trace_info.keys())
         if not all(k in trace_keys for k in _REQUIRED_KEYS):
             return False
         if trace_keys.difference(_REQUIRED_KEYS + _OPTIONAL_KEYS):
diff --git a/requirements.txt b/requirements.txt
index de2d919..954148d 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -4,6 +4,5 @@ oslo.serialization>=2.18.0 # Apache-2.0
 oslo.utils>=3.33.0 # Apache-2.0
 PrettyTable>=0.7.2 # BSD
 requests>=2.14.2 # Apache-2.0
-six>=1.10.0 # MIT
 WebOb>=1.7.1 # MIT
 importlib_metadata>=1.7.0;python_version<'3.8' # Apache-2.0