diff --git a/lower-constraints.txt b/lower-constraints.txt
index f137ec0..4d86aa1 100644
--- a/lower-constraints.txt
+++ b/lower-constraints.txt
@@ -49,7 +49,6 @@ python-subunit==1.0.0
 requests==2.14.2
 requests-mock==1.1.0
 rfc3986==0.3.1
-six==1.10.0
 stestr==2.0.0
 testscenarios==0.4
 testtools==2.2.0
diff --git a/octaviaclient/tests/fakes.py b/octaviaclient/tests/fakes.py
index 5676e76..661e92f 100644
--- a/octaviaclient/tests/fakes.py
+++ b/octaviaclient/tests/fakes.py
@@ -21,7 +21,6 @@ from oslo_serialization import jsonutils
 
 from keystoneauth1 import fixture
 import requests
-import six
 
 
 AUTH_TOKEN = "foobar"
@@ -244,7 +243,7 @@ class FakeResponse(requests.Response):
 
         self.headers.update(headers)
         self._content = jsonutils.dumps(data)
-        if not isinstance(self._content, six.binary_type):
+        if not isinstance(self._content, bytes):
             self._content = self._content.encode()
 
 
diff --git a/releasenotes/notes/drop-python-2-7-7b427838d72ef248.yaml b/releasenotes/notes/drop-python-2-7-7b427838d72ef248.yaml
new file mode 100644
index 0000000..20d6af3
--- /dev/null
+++ b/releasenotes/notes/drop-python-2-7-7b427838d72ef248.yaml
@@ -0,0 +1,5 @@
+---
+upgrade:
+  - |
+    Python 2.7 support has been dropped. The minimum version of Python now
+    supported by python-octaviaclient is Python 3.6.
diff --git a/requirements.txt b/requirements.txt
index 5cb24d8..b46f09b 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -12,4 +12,3 @@ oslo.serialization!=2.19.1,>=2.18.0 # Apache-2.0
 oslo.utils>=3.33.0 # Apache-2.0
 pbr!=2.1.0,>=2.0.0 # Apache-2.0
 requests>=2.14.2 # Apache-2.0
-six>=1.10.0 # MIT
diff --git a/setup.cfg b/setup.cfg
index 64d59c1..1480f5b 100644
--- a/setup.cfg
+++ b/setup.cfg
@@ -13,8 +13,6 @@ classifier =
     License :: OSI Approved :: Apache Software License
     Operating System :: POSIX :: Linux
     Programming Language :: Python
-    Programming Language :: Python :: 2
-    Programming Language :: Python :: 2.7
     Programming Language :: Python :: 3
     Programming Language :: Python :: 3.6
     Programming Language :: Python :: 3.7
diff --git a/tox.ini b/tox.ini
index 6cbcb2f..b40efa1 100644
--- a/tox.ini
+++ b/tox.ini
@@ -1,9 +1,10 @@
 [tox]
 minversion = 2.5.0
-envlist = py27,py37,pep8
+envlist = py37,pep8
 skipsdist = True
 
 [testenv]
+basepython = python3
 usedevelop = True
 whitelist_externals =
     find
@@ -21,15 +22,12 @@ commands =
     stestr slowest
 
 [testenv:pep8]
-basepython = python3
 commands = flake8 {posargs}
 
 [testenv:venv]
-basepython = python3
 commands = {posargs}
 
 [testenv:cover]
-basepython = python3
 setenv =
   {[testenv]setenv}
   PYTHON=coverage run --source octaviaclient --parallel-mode
@@ -45,7 +43,6 @@ commands =
   coverage report --fail-under=90 --skip-covered
 
 [testenv:docs]
-basepython = python3
 deps =
   -c{env:UPPER_CONSTRAINTS_FILE:https://releases.openstack.org/constraints/upper/master}
   -r{toxinidir}/requirements.txt
@@ -55,7 +52,6 @@ commands =
   sphinx-build -W -b html doc/source doc/build/html
 
 [testenv:pdf-docs]
-basepython = python3
 deps = {[testenv:docs]deps}
 whitelist_externals =
   make
@@ -66,7 +62,6 @@ commands =
   make -C doc/build/pdf
 
 [testenv:releasenotes]
-basepython = python3
 deps =
   -c{env:UPPER_CONSTRAINTS_FILE:https://releases.openstack.org/constraints/upper/master}
   -r{toxinidir}/requirements.txt
@@ -76,7 +71,6 @@ commands =
   sphinx-build -a -E -W -d releasenotes/build/doctrees -b html releasenotes/source releasenotes/build/html
 
 [testenv:debug]
-basepython = python3
 passenv = OS_*
 commands =
     pip install -q -U ipdb
@@ -92,14 +86,12 @@ exclude=.venv,.git,.tox,dist,doc,*lib/python*,*egg,build
 local-check-factory = octaviaclient.hacking.checks.factory
 
 [testenv:lower-constraints]
-basepython = python3
 deps =
   -c{toxinidir}/lower-constraints.txt
   -r{toxinidir}/test-requirements.txt
   -r{toxinidir}/requirements.txt
 
 [testenv:requirements]
-basepython = python3
 deps =
   -egit+https://opendev.org/openstack/requirements#egg=openstack-requirements
 whitelist_externals = sh
diff --git a/zuul.d/projects.yaml b/zuul.d/projects.yaml
index 88dd382..0952755 100644
--- a/zuul.d/projects.yaml
+++ b/zuul.d/projects.yaml
@@ -3,8 +3,7 @@
       - check-requirements
       - openstack-cover-jobs
       - openstack-lower-constraints-jobs
-      - openstack-python-jobs
-      - openstack-python3-train-jobs
+      - openstack-python3-ussuri-jobs
       - openstackclient-plugin-jobs
       - publish-openstack-docs-pti
       - release-notes-jobs-python3